Coronavirus–ACE2 Cell-Entry Screen
Can the model reason accurately about difficult scientific material?
Top rankings
One row per model, using its best reported score across effort settings.
Effort curve
Every sourced cost-linked effort value for this exact version. Lines connect complete sweeps only.
Definition and comparison boundaryinternal methodology
Can the model reason accurately about difficult scientific material?
Scientific knowledge and reasoning under the benchmark's published question set. Higher is better. Composite score reported by OpenAI for held-out cell-entry measurements.
This is a publisher-defined internal evaluation. The task set or grading details are not fully public, so treat it as directional evidence.
OpenAI reports GPT-6 Astra at 0.42 versus GPT-5.6 Sol at 0.43 on an unpublished dataset involving three bat coronaviruses and 35 mammalian ACE2 proteins; a helpful-only Astra model is 0.45 and is retained separately.
Method / source